Achievements Over A Decade
On a regular basis, the Centre caters to the need of more than 250 biomedical research institutions including public and private enterprises. The Centre has so far bred and supplied more than one million laboratory animals to biomedical research institutions in the country for basic and applied research.
In addition, standard laboratory animal chow based on locally available ingredients has been developed for rodents, rabbits and monkeys and it is being supplied regularly to various research institutions on request. Also special experimental, feeds as per the requirements like high fat diets, iron and zinc deficient diets etc. are also being supplied.
The Centre regularly supplies tissues, blood and blood products of laboratory animals to several research institutions throughout the country.
It has so far trained more than 2000 candidates on various aspects of laboratory animal care, breeding, husbandry, animal experimentation, ethics, rules and regulations under 2 of its regular annual training courses from 1967. It has also trained more than 600 research scientists in the proper use of animals for experimentation under adhoc training programmes over the years.
It has also conducted international seminars/workshops and held several national seminars over the years. The Centre has brought out number of News letters on various aspects of laboratory animal sciences and distributed them on gratis to several research institutes/organizations all over the country. It has also brought out a publication called "Laboratory Animals User’s Guide" which is a ready reckoner for the laboratory animal planners and researchers.
The Centre acted at an advisory capacity in setting up of several new laboratory animal facilities in the country developed under private and government sectors as per CPCSEA and AAALAC norms.
The Centre has recently developed 3 mutant obese rat models WNIN ob/ob, WNIN GRob and SD hairless mutant strains for basic research on obesity and associated degenerated diseases like diabetes, cataract, infertility, ageing and dermatological studies. These models have some unique characteristics, which are not seen in similar models available abroad. Centre had collaborative studies with Rockefeller University, New York, US, that are in progress to identify the gene causing obesity in these animals.
The Centre has taken up to collect base line data on clinical biochemical profile along with physiological parameters of various laboratory animals maintained, for supply as a reference material to research workers.
The Centre is a member of the Advanced Pre-clinical toxicological research centre, which is established at NIN, in 2005, to help carrying out pre clinical toxicological evaluation of drugs, vaccines, nutroceuticals, genetically modified foods for government and private entrepreneurs.
The Centre has created an animal physiology laboratory and primate experimentation faciliy. Plans are now for creating a transgenic and knock out animal facility, meant for research purpose in house as well as outside.
New research projects are being initiated linking obesity with asthma, obesity and iron metabolism, obesogemic diets and their impact on genome, influence of microflora on obesity, obesity and nesfatin (the new satiety molecule identified).
The Centre will be merged with the newly established institute NARFBR under ICMR.